This first panel session will provide a high-level overview of the nuclear decommissioning and clean-up challenges in the UK against the backdrop of managing the legacy situation, the existing nuclear programme and the advent of new nuclear build. This panel will discuss the roles of Government policy, NDA strategy, implementation at the site level and the importance of strong but flexible regulation. The special relationship between the US DOE and the UK NDA will also be discussed with particular emphasis on the collaboration between the two Governments on innovative technology development and implementation, operational lessons learned and management approaches.